Label-free luminescence switch-on detection of hepatitis C virus NS3 helicase activity using a G-quadruplex-selective probe† †Electronic supplementary information (ESI) available: Compound characterisation and supplementary data. See DOI: 10.1039/c4sc03319a Click here for additional data file.

Luminescence switch-on detection of protein tyrosine kinase-7 using a G-quadruplex-selective probe† †Electronic supplementary information (ESI) available: Compound characterisation and supplementary data. See DOI: 10.1039/c5sc01320h Click here for additional data file.

Department of Chemistry, Hong Kong Bapti China. E-mail: [email protected] State Key Laboratory of Quality Research i Medical Sciences, University of Macau, Ma mo University of Bordeaux, ARNA Laboratory [email protected] INSERM, U869, IECB, Pessac, France Partner State Key Laboratory of Environme Baptist University, Kowloon Tong, Hong Kon † Electronic supplementary informa characterisation and...

Selective glycoprotein detection through covalent templating and allosteric click-imprinting† †Electronic supplementary information (ESI) available: Synthetic procedures, synthesis of DFC, NMR spectra, surface modification and characterisation in addition to SPR analysis. See DOI: 10.1039/c5sc02031j Click here for additional data file.

Conjugating a groove-binding motif to an Ir(iii) complex for the enhancement of G-quadruplex probe behavior† †Electronic supplementary information (ESI) available: Compound characterisation and supplementary data. See DOI: 10.1039/c6sc00001k Click here for additional data file.

a Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China. Email: [email protected] bState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China. Email: [email protected] cDepartment of Biology and Chemistry, City University of Hong Kong, Kowloon Tong, Hong Kong, China dUniversity of Bo...

Enantioselective Narasaka–Heck cyclizations: synthesis of tetrasubstituted nitrogen-bearing stereocenters† †Electronic supplementary information (ESI) available: Experimental procedures and characterisation data for all compounds are provided. CCDC 1438659 and 1438660. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc04466b Click here for additional data file. Click here for additional data file.

School of Chemistry, University of Bristol, B bris.ac.uk AstraZeneca, Alderley Park, Maccleseld, C AstraZeneca, Pepparedsleden 1, Mölndal, 4 † Electronic supplementary information ( and characterisation data for all compou 1438660. For ESI and crystallographic dat DOI: 10.1039/c6sc04466b ‡ These authors contributed equally. § Author to whom correspondence shou structures of 3b and Pd[(Sa,S)-L-...

A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase† †Electronic supplementary information (ESI) available: Structures and characterisation for all MK compounds. Full characterisation data (NMR, HR-MS) for all SODO derivatives. See DOI: 10.1039/c6cc00095a Click here for additional data file.

Copper/zinc superoxide dismutase (Cu/Zn SOD) is an essential enzyme that protects tissue from oxidative damage. Herein we report the first fluorogenic probe (SODO) for the detection and in vivo imaging of Cu/Zn SOD. SODO represents a unique chemical probe for translational imaging studies of Cu/Zn SOD in inflammatory disorders.